Bone marrow aspirate, W-G stain, low power showing packed marrowBone marrow aspirate, W-G stain, low power showing packed marrow
Higher power showing blasts with basophilic cytoplasm, occasional surface blebs, and megaloblastoid erythroid changesHigher power showing blasts with basophilic cytoplasm, occasional surface blebs, and megaloblastoid erythroid changes
Peripheral smear, W-G stain, showing blasts with variably abundant blue cytoplasm, and erythroids with megaloblastoid changePeripheral smear, W-G stain, showing blasts with variably abundant blue cytoplasm, and erythroids with megaloblastoid change
Bone marrow biopsy, H&E stain, showing dysplastic megakaryocytes and blasts. Note two dysplastic megakaryocytes (upper right and lower central) with eosinophilic cytoplasmic mass displacing nucleus.Bone marrow biopsy, H&E stain, showing dysplastic megakaryocytes and blasts. Note two dysplastic megakaryocytes (upper right and lower central) with eosinophilic cytoplasmic mass displacing nucleus.
Note similar dysplastic megakaryocytes with central masses, center of photomicrograph and lower rightNote similar dysplastic megakaryocytes with central masses, center of photomicrograph and lower right
Similar dysplastic megakaryocyte, upper right, with 2 masses without visible attached cytoplasm or nuclei, lower rightSimilar dysplastic megakaryocyte, upper right, with 2 masses without visible attached cytoplasm or nuclei, lower right
Bone marrow aspirate, W-G stain, showing similar megakaryocyte with this preparation.Bone marrow aspirate, W-G stain, showing similar megakaryocyte with this preparation.