High power view of H&E stained lymph node section showing uniform small cells with numerous mitosesHigh power view of H&E stained lymph node section showing uniform small cells with numerous mitoses
Flow cytometric analysis showing aberrant population expressing TdT, CD1a, cytoplasmic CD3, CD2, CD4, CD5, CD7, and CD8 (red).Flow cytometric analysis showing aberrant population expressing TdT, CD1a, cytoplasmic CD3, CD2, CD4, CD5, CD7, and CD8 (red).
FISH with BCR/ABL dual fusion probe showing atypical pattern with three fusion signalsFISH with BCR/ABL dual fusion probe showing atypical pattern with three fusion signals
Cytogenetic analysis of lymph node showing complex karyotype with translocation (9;22)(Philadelphia), an additional Philadelphia chromosome, trisomy 8, trisomy 19 and deletion of the long arm of chromosome 4 (4q-)Cytogenetic analysis of lymph node showing complex karyotype with translocation (9;22)(Philadelphia), an additional Philadelphia chromosome, trisomy 8, trisomy 19 and deletion of the long arm of chromosome 4 (4q-)