Low power view of paraspinal mass biopsy. Sections show lymphoblast infiltration that are intermediate in size with fine chromatin, irregular nuclear contours, and scant cytoplasm. Numerous tingible body macrophages are seen.Low power view of paraspinal mass biopsy. Sections show lymphoblast infiltration that are intermediate in size with fine chromatin, irregular nuclear contours, and scant cytoplasm. Numerous tingible body macrophages are seen.
High power view of paraspinal mass biopsy. Sections show lymphoblast infiltration that are intermediate in size with fine chromatin, irregular nuclear contours, and scant cytoplasm. Numerous tingible body macrophages are seen.High power view of paraspinal mass biopsy. Sections show lymphoblast infiltration that are intermediate in size with fine chromatin, irregular nuclear contours, and scant cytoplasm. Numerous tingible body macrophages are seen.
Peripheral blood smear shows leukocytosis with absolute neutrophilia and absolute eosinophilia. The granulocytes are left shifted, including rare blasts, and show reactive changes, including toxic granulation and vacuolization. The eosinophils show reactive or atypical features, including hyperlobation, polarization of granules, degranulation, and cytoplasmic vacuolizationPeripheral blood smear shows leukocytosis with absolute neutrophilia and absolute eosinophilia. The granulocytes are left shifted, including rare blasts, and show reactive changes, including toxic granulation and vacuolization. The eosinophils show reactive or atypical features, including hyperlobation, polarization of granules, degranulation, and cytoplasmic vacuolization
Peripheral blood smear shows leukocytosis with absolute neutrophilia and absolute eosinophilia. The granulocytes are left shifted, including rare blasts, and show reactive changes, including toxic granulation and vacuolization. The eosinophils show reactive or atypical features, including hyperlobation, polarization of granules, degranulation, and cytoplasmic vacuolizationPeripheral blood smear shows leukocytosis with absolute neutrophilia and absolute eosinophilia. The granulocytes are left shifted, including rare blasts, and show reactive changes, including toxic granulation and vacuolization. The eosinophils show reactive or atypical features, including hyperlobation, polarization of granules, degranulation, and cytoplasmic vacuolization
Bone marrow core biopsy shows myeloid hyperplasia with a left shift in granulocyte maturation and increased eosinophilsBone marrow core biopsy shows myeloid hyperplasia with a left shift in granulocyte maturation and increased eosinophils
Bone marrow core biopsy shows myeloid hyperplasia with a left shift in granulocyte maturation and increased eosinophilsBone marrow core biopsy shows myeloid hyperplasia with a left shift in granulocyte maturation and increased eosinophils
Bone marrow core biopsy shows myeloid hyperplasia with a left shift in granulocyte maturation and increased eosinophilsBone marrow core biopsy shows myeloid hyperplasia with a left shift in granulocyte maturation and increased eosinophils
Bone marrow core biopsy shows myeloid hyperplasia with a left shift in granulocyte maturation and increased eosinophilsBone marrow core biopsy shows myeloid hyperplasia with a left shift in granulocyte maturation and increased eosinophils
IHC for MPO shows myeloid hyperplasia. IHC for CD34 highlights rare scattered blats (1-2% of bone marrow cellularity). A reticulin stain highlights mild reticulin fibrosisIHC for MPO shows myeloid hyperplasia. IHC for CD34 highlights rare scattered blats (1-2% of bone marrow cellularity). A reticulin stain highlights mild reticulin fibrosis
Immature eosinophilic precursors with occasional basophilic granulesImmature eosinophilic precursors with occasional basophilic granules
Immature eosinophilic precursors with occasional basophilic granulesImmature eosinophilic precursors with occasional basophilic granules