Peripheral blood smear showing a Pelger-Huet-like neutrophil (left), a blast (middle), and an abnormal monocyte (right).Peripheral blood smear showing a Pelger-Huet-like neutrophil (left), a blast (middle), and an abnormal monocyte (right).
Bone marrow trephine biopsy. Left: PAS stain showing ALIP. Right: Immunohistochemical stain for CD34.Bone marrow trephine biopsy. Left: PAS stain showing ALIP. Right: Immunohistochemical stain for CD34.
Immunohistochemical stain for MPO on the bone marrow trephine biopsy. Blasts and maturing myeloid cells positive.Immunohistochemical stain for MPO on the bone marrow trephine biopsy. Blasts and maturing myeloid cells positive.
Immunohistochemical stain for CD138 on the trephine biopsy shows increased plasma cells.Immunohistochemical stain for CD138 on the trephine biopsy shows increased plasma cells.
Bone marrow aspirate smear. 400X.Bone marrow aspirate smear. 400X.
Bone marrow aspirate smear. 1,000X.Bone marrow aspirate smear. 1,000X.
Iron stain shows increased iron stores. Inset: Ring sideroblast.Iron stain shows increased iron stores. Inset: Ring sideroblast.
Karyotyping shows abnormal cytogenetic finding: 46,XY,der(11)t(3;11)(q12;q21).Karyotyping shows abnormal cytogenetic finding: 46,XY,der(11)t(3;11)(q12;q21).