Some areas were composed mainly of large blasts with abundant cytoplasm. They expressed CD117 and MPO, but not lymphoid antigens.Some areas were composed mainly of large blasts with abundant cytoplasm. They expressed CD117 and MPO, but not lymphoid antigens.
Other areas were composed mainly of small blasts with scant cytoplasm. They expressed B cell antigens, including PAX5, CD79a and CD20. They did not express CD117 or MPO.Other areas were composed mainly of small blasts with scant cytoplasm. They expressed B cell antigens, including PAX5, CD79a and CD20. They did not express CD117 or MPO.
10 color flow cytometric analysis showed separate, distinct populations. One population had a myeloid phenotype with CD34 and CD13, but not CD10 or CD19. The second population expressed CD10 and CD19, but not CD34 or CD13.10 color flow cytometric analysis showed separate, distinct populations. One population had a myeloid phenotype with CD34 and CD13, but not CD10 or CD19. The second population expressed CD10 and CD19, but not CD34 or CD13.