Figures 1A and 1B. Extensive involvement of bilateral maxillary condyles by an diffuse atypical cell infiltrates. Figures 1A and 1B. Extensive involvement of bilateral maxillary condyles by an diffuse atypical cell infiltrates.
Figure 2. Neoplastic cells are discohesive and mononuclear with extensive artifact, mandibular condyle. Figure 2. Neoplastic cells are discohesive and mononuclear with extensive artifact, mandibular condyle.
Figure 3. Neoplastic cells are strongly positive for CD33, CD43 and MPO and negative for keratin, CD34 and CD117. Figure 3. Neoplastic cells are strongly positive for CD33, CD43 and MPO and negative for keratin, CD34 and CD117.
Figure 4. Peripheral blood smears displaying circulating large immature myeloid cells with open chromatin, irregular nuclear contours and some prominent nucleoli.Figure 4. Peripheral blood smears displaying circulating large immature myeloid cells with open chromatin, irregular nuclear contours and some prominent nucleoli.
Figure 5. Peripheral blood flow cytometry demonstrating CD117, CD33 and dim CD13 expression in blast population with no CD34 expression. Figure 5. Peripheral blood flow cytometry demonstrating CD117, CD33 and dim CD13 expression in blast population with no CD34 expression.
Figures 6A and 6B. Bone marrow aspirate smear displaying (>60% of total cells) high blast count in the background of dysplastic changes in erythroid and megakaryocytic lineages.Figures 6A and 6B. Bone marrow aspirate smear displaying (>60% of total cells) high blast count in the background of dysplastic changes in erythroid and megakaryocytic lineages.
Figure 7. Cellular bone marrow core biopsy with large clusters of blasts.Figure 7. Cellular bone marrow core biopsy with large clusters of blasts.
Figure 8. Flow cytometry performed on bone marrow aspirate shows similar phenotype to that of shown in peripheral blood analysis; CD33+, CD117+ and dimCD13+, CD34-.Figure 8. Flow cytometry performed on bone marrow aspirate shows similar phenotype to that of shown in peripheral blood analysis; CD33+, CD117+ and dimCD13+, CD34-.