Wright-stained peripheral blood smear demonstrates circulating blasts and thrombocytosis Wright-stained peripheral blood smear demonstrates circulating blasts and thrombocytosis
Wright-stained bone marrow aspirate smear demonstrates increased blasts and residual maturing hematopoietic cellsWright-stained bone marrow aspirate smear demonstrates increased blasts and residual maturing hematopoietic cells
H&E-stained bone marrow trephine biopsy shows a hypercellular marrow with numerous blasts and increased atypical appearing megakaryocytesH&E-stained bone marrow trephine biopsy shows a hypercellular marrow with numerous blasts and increased atypical appearing megakaryocytes
Representative histogram of flow cytometry showing blasts with expression of TdT and dim CD79A Representative histogram of flow cytometry showing blasts with expression of TdT and dim CD79A
Post treatment quantitative real time PCR at the time of disease relapse detects b2-b3 type BCR-ABL1 transcripts (green-colored amplification curves) with a BCR-ABL1/ABL1 ratio of 0.0075 Post treatment quantitative real time PCR at the time of disease relapse detects b2-b3 type BCR-ABL1 transcripts (green-colored amplification curves) with a BCR-ABL1/ABL1 ratio of 0.0075