Peripheral blood, Wright Giemsa stained, 60x. Increased numbers of left shifted myeloids with rare blasts present. Hypolobate and hypogranular neutrophils were also noted.Peripheral blood, Wright Giemsa stained, 60x. Increased numbers of left shifted myeloids with rare blasts present. Hypolobate and hypogranular neutrophils were also noted.
Bone marrow aspirate, Wright-Giemsa, 60x. Left shifted myelogenesis with rare (1%) blasts present.Bone marrow aspirate, Wright-Giemsa, 60x. Left shifted myelogenesis with rare (1%) blasts present.
Flow cytometry findings: 1% CD34-positive blasts were noted on flow cytometry, a subset of which express CD56 and CD19.Flow cytometry findings: 1% CD34-positive blasts were noted on flow cytometry, a subset of which express CD56 and CD19.
Interphase chromosome analysis showing the t(8;21) translocation.Interphase chromosome analysis showing the t(8;21) translocation.
FISH dual-fusion probe analysis confirming the t(8;21) translocation. The translocation was present in 21 of 21 metaphases analyzed.FISH dual-fusion probe analysis confirming the t(8;21) translocation. The translocation was present in 21 of 21 metaphases analyzed.