Bone marrow core biopsy demonstrates a hypercellular marrow with trilineage hypoplasia and markedly increased immature cells (H&E, x200). Bone marrow core biopsy demonstrates a hypercellular marrow with trilineage hypoplasia and markedly increased immature cells (H&E, x200).
Bone marrow aspirate smear shows a cluster of blasts and a dysplastic granulocyte (Wright-Gimesa, x1000).Bone marrow aspirate smear shows a cluster of blasts and a dysplastic granulocyte (Wright-Gimesa, x1000).
A representative karyotype shows 46,XY,t(1;3)(p36;p21). The arrows indicate translocations between chromosomes 1p36 and 3p21.A representative karyotype shows 46,XY,t(1;3)(p36;p21). The arrows indicate translocations between chromosomes 1p36 and 3p21.