2010 - Bone marrow aspirate. Large atypical cells with irregular and polylobated nuclei.2010 - Bone marrow aspirate. Large atypical cells with irregular and polylobated nuclei.
Low power (5x) of bone marrow aspirate showing mononuclear infiltrate.Low power (5x) of bone marrow aspirate showing mononuclear infiltrate.
CD20 immunohistochemical stain is positive in large atypical cells. CD20 immunohistochemical stain is positive in large atypical cells.
CD79a immunohistochemical stain is positive in neoplastic cells.CD79a immunohistochemical stain is positive in neoplastic cells.
PAX5 immunohistochemical stain is positive in neoplastic cells confirming B cell lineage. Stain for CD34 and TdT are negative.PAX5 immunohistochemical stain is positive in neoplastic cells confirming B cell lineage. Stain for CD34 and TdT are negative.
Bone marrow H&E (5x): The marrow is replaced by a mononuclear infiltrate. Bone marrow H&E (5x): The marrow is replaced by a mononuclear infiltrate.
Bone marrow biopsy H&E (20x): Area in bone marrow with tumor necrosis, ghost cells are seen.Bone marrow biopsy H&E (20x): Area in bone marrow with tumor necrosis, ghost cells are seen.
Bone marrow biopsy H&E (40x): High power of neoplastic cells with hyperchromatic nuclei.Bone marrow biopsy H&E (40x): High power of neoplastic cells with hyperchromatic nuclei.
2011: Bone marrow aspirate showing a diffuse infiltrate of mononuclear cells consistent with blasts. Virtually no trilineage hematopoiesis is present.2011: Bone marrow aspirate showing a diffuse infiltrate of mononuclear cells consistent with blasts. Virtually no trilineage hematopoiesis is present.
Bone marrow aspirate: Blasts with scant to moderate basophilic cytoplasm, round to irregular nuceli and fine chromatin. Bone marrow aspirate: Blasts with scant to moderate basophilic cytoplasm, round to irregular nuceli and fine chromatin.
Bone marrow aspirate: Blasts with round to irregular nuclei, fine chromatin and a blush of azurophilic granules in the cytoplasm. The blasts demonstrated the following immunophenotype: positive for CD13, CD33, CD4, CD14, CD11b, CD38, CD34, CD15, MPO.Bone marrow aspirate: Blasts with round to irregular nuclei, fine chromatin and a blush of azurophilic granules in the cytoplasm. The blasts demonstrated the following immunophenotype: positive for CD13, CD33, CD4, CD14, CD11b, CD38, CD34, CD15, MPO.