Figure 1a: Peripheral blood smear highlighting blast morphology (1000x magnification).
Figure 1b: Peripheral blood smear highlighting blast morphology (1000x magnification).
Figure 1c: Peripheral blood smear highlighting blast morphology (1000x magnification).
Figure 1d: Peripheral blood smear highlighting blast morphology (1000x magnification).
Figure 2: Bone marrow aspirate smear with increased blasts (1000x magnification).
Figure 3: Bone marrow core biopsy showing hypercellular marrow (100x magnification).
Figure 4: Bone marrow core biopsy with sheets of immature cells (400x magnification).
Figure 5(CD3): Immunohistochemistry of bone marrow clot sections (400x magnification).
Figure 5(CD7): Immunohistochemistry of bone marrow clot sections (400x magnification).
Figure 5(TdT): Immunohistochemistry of bone marrow clot sections (400x magnification).
Figure 5(MPO): Immunohistochemistry of bone marrow clot sections (400x magnification).
Figure 6a: Flow cytometry, peripheral blood. Blasts (red) are CD45+ (moderate), CD7+, CD11b+, CD34+, and CD117+ (partial). Surface CD3 is negative.
Figure 6b: Flow cytometry, peripheral blood. Blasts (red) are CD45+ (moderate), CD7+, CD11b+, CD34+, and CD117+ (partial). Surface CD3 is negative.
Figure 6c: Flow cytometry, peripheral blood. Blasts (red) are CD45+ (moderate), CD7+, CD11b+, CD34+, and CD117+ (partial). Surface CD3 is negative.
Figure 6d: Flow cytometry, peripheral blood. Blasts (red) are CD45+ (moderate), CD7+, CD11b+, CD34+, and CD117+ (partial). Surface CD3 is negative.
Figure 7a: Flow cytometry (cont.). Two blast population subsets with differing HLA-DR and CD99 expression. Very dim cCD3 and TdT positive subsets are seen. Blasts are negative for MPO.
Figure 7b: Flow cytometry (cont.). Two blast population subsets with differing HLA-DR and CD99 expression. Very dim cCD3 and TdT positive subsets are seen. Blasts are negative for MPO.
Figure 7c: Flow cytometry (cont.). Two blast population subsets with differing HLA-DR and CD99 expression. Very dim cCD3 and TdT positive subsets are seen. Blasts are negative for MPO.
Figure 7d: Flow cytometry (cont.). Two blast population subsets with differing HLA-DR and CD99 expression. Very dim cCD3 and TdT positive subsets are seen. Blasts are negative for MPO.