Lymphoblasts on touch prep of bone marrow aspirate.
Core biopsy with extensive necrosis.
Core biopsy with extensive necrosis and collections of blasts.
Lymph node.
Lymph node with necrosis and blasts.
Core biopsy from June 2012. Necrosis and blasts present.
Core biopsy from June 2012. Blasts present.
Aspirate from June 2012. Rare hemophagocytosis present.
Representative flow cytometry plots from lymph node biopsy. Population of blasts with the same immunophenotype was seen in BM flow.
Immunohistochemistry performed retrospectively on outside biopsy from June 2012 revealing involvement by T lymphoblastic leukemia at the time of the initial HLH diagnosis.
Immunostain for CD99 (consensus group additional study)